After some sound advice from suppliers I have began a trial of the Citrix NetScaler VPX virtual load balancer and thus far I have been impressed. All of the features I have used in the F5 range are available and then some. Thus far the only issue I have found is the information provided by Citrix on how to configure their product for exchange 2010 is not up to date. Relying on community Blog posts, configuring the Load Balancer has not been too difficult. I will say that without expert advice on how to avoid the gotcha's associated with the product, one might spend a substantial amount of time attempting to configure a feature in a unsupported manner. This however was also the case with our F5's I previously worked on.
We have not began our migration from Exchange 2003 yet so with only 4 users testing the exchange system performance opinions have not been formed however using the Microsoft Exchange 2010 Load Generator, the 200mbs licenced product has easily coped with a suitably configured test.
I will update this post with further findings as the migration progresses.